Development of oral controlled release products

Challenge: A multi-national drug delivery company with expertise in oral delivery identified opportunity in controlled delivery for specific indications using the oral route.  PharmaCRO was brought in to help generate novel product concepts, and to guide the formulation development effort

Solution: PharmaCRO worked with the client development team to identify and develop a liquid formulation for improved pediatric compliance, and a time-release oral dose formulation containing two drugs with different lag times for release (chronotherapeutics) for the treatment of nocturnal acid breakthrough

Result: The formulations were successfully developed to meet the requirements of the target product profile